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CME / CE

Recognizing the Significance of Pseudomonas aeruginosa Resistance: Where Do We Stand Today?

  • Authors: Keith S. Kaye, MD, MPH; Keith A. Rodvold, PharmD, FCCP, FIDSA
  • CME / CE Released: 10/24/2016
  • THIS ACTIVITY HAS EXPIRED
  • Valid for credit through: 10/24/2017
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Target Audience and Goal Statement

Target Audience

This continuing medical education activity is planned to meet the need of healthcare providers in a variety of practice settings, including large and small health systems, outpatient clinics, managed-care organizations, long-term care facilities, and academia. This activity is especially beneficial for healthcare professionals (including physicians, pharmacists, and nurse practitioners) who manage patients with or at-risk for serious bacterial infections.

Educational Overview

Pseudomonas aeruginosa is a leading cause of healthcare-associated infections in hospitals in the United States. P. aeruginosa frequently exhibits antimicrobial resistance and multidrug resistance, which presents a therapeutic challenge to clinicians. This versatile pathogen utilizes a variety of resistance mechanisms that often render currently available antimicrobials ineffective. The presence of resistance and multidrug resistance has significant consequences on outcomes, including increased mortality rates and healthcare costs.

The Centers for Disease Control and Prevention (CDC) has identified multidrug-resistant (MDR) P. aeruginosa as a serious healthcare threat. To better understand the scope of P. aeruginosa resistance, the CDC made available the Antibiotic Resistance Patient Safety Atlas (http://gis.cdc.gov/grasp/PSA/MapView.html). This interactive online tool provides antibiotic-resistance data from a national, regional, or state level for device- and procedure-related bacterial infections. Resistance data were compiled from over 4400 healthcare institutions reporting to the CDC National Healthcare Safety Network (NHSN) from 2011 to 2014. Online users can analyze data related to 31 resistance phenotypes of various bacteria commonly encountered in acute care settings. The Atlas clearly illustrates the crisis of antimicrobial resistance in US hospitals, particularly resistant and MDR P. aeruginosa.

This program aims to build awareness of the prevalence of antimicrobial-resistant and MDR P. aeruginosa in US hospitals and the challenges associated with this pathogen. Interprofessional expert faculty (Keith S. Kaye, MD, Professor of Medicine, University of Michigan Medical School, and Keith A. Rodvold, PharmD, Professor of Pharmacy Practice and Medicine, University of Illinois at Chicago) provide the most up-to-date information on:

  • Epidemiology and burden of P. aeruginosa infections
  • P. aeruginosa mechanisms of resistance
  • CDC Patient Safety Atlas data on antimicrobial-resistant P. aeruginosa
  • In vitro susceptibility data of current antipseudomonal agents
     

Upon completion of this activity, participants will be able to:

  1. Describe the unique characteristics of P. aeruginosa and the challenges associated with managing serious infections caused by this organism
  2. Identify the various mechanisms utilized by P. aeruginosa that enable this pathogen to exhibit resistance to commonly used antimicrobial agents
  3. Interpret the latest CDC surveillance data on the prevalence of resistant and multidrug-resistant P. aeruginosa infections at local, regional, and national levels


Disclosures

Disclosure of Conflicts of Interest

In accordance with policies set forth by the Accreditation Council for Continuing Medical Education (ACCME), Center for Independent Healthcare Education requires all faculty members and spouses/significant others with an opportunity to affect the content of a continuing education activity to disclose any relevant financial relationships during the past 12 months with commercial interests. A commercial interest is any entity producing, marketing, reselling, or distributing healthcare goods or services consumed by or used on patients. Relationships with commercial interests and conflicts of interest resulting from those relationships must be revealed to the audience and resolved prior to the activity.

Relevant relationships include roles such as speaker, author, consultant, independent contractor (including research), employee, investor, advisory committee member, board member, review panelist, and investigator. If a potential speaker or author indicates a possible conflict of interest, the conflict will be resolved by choosing another speaker or author for that topical area, or the slides, handouts, and/or monograph will be reviewed and approved by a qualified commercially disinterested peer.

Faculty

Keith S. Kaye, MD, MPH

Professor of Medicine, Division of Infectious Diseases, Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, Michigan

Disclosure: Keith S. Kaye, MD, MPH, has disclosed the following relevant financial relationships with commercial interests:
Advisory Board and Consultant: Merck & Co., Pfizer, Inc., The Medicines Co.; Research Support: Merck and Co.
Dr. Kaye does not discuss the off-label use of a product.

Keith A. Rodvold, PharmD, FCCP, FIDSA

Professor of Pharmacy Practice and Medicine, Colleges of Pharmacy and Medicine, University of Illinois at Chicago, Chicago, Illinois

Disclosure: Keith A. Rodvold, PharmD, FCCP, FIDSA, has disclosed the following relevant financial relationships with commercial interests:
Advisory Board: The Medicines Co., Bayer, Paratek, Theravance, Achoagen, Melinta, Shionogi, Zavanta; Consultant: Paratek, Theravance, Spero Therapeutics, Zavanta, Wockhardt; Research Support: Theravance, Allergan; Speaker's Bureau: The Medicines Co., Allergan, Merck & Co.; Safety Monitoring Board: Janssen.
Dr. Rodvold does not discuss the off-label use of a product.

Additional Planners/Reviewers affiliation and disclosure statements:

No (other) speakers, authors, planners, or content reviewers have any relevant financial relationships to disclose.
No (other) speakers or authors will discuss off-label use of a product.

Content review confirmed that the content was developed in a fair, balanced manner free from commercial bias. Disclosure of a relationship is not intended to suggest or condone commercial bias in any presentation, but it is made to provide participants with information that might be of potential importance to their evaluation of a presentation.



Accreditation Statements

    For Physicians

  • This activity is jointly provided by Center for Independent Healthcare Education and Vemco MedEd and in collaboration with the National Foundation for Infectious Diseases.

    This activity has been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education through the joint providership of the Center for Independent Healthcare Education (Center) and Vemco MedEd. Center is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.

    Center designates this enduring material for a maximum of 1.0 AMA PRA Category 1 Credit™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

    Contact This Provider

    For Pharmacists

  • Center for Independent Healthcare Education is accredited by the Accreditation Council for Pharmacy Education as a provider for continuing pharmacy education. Center for Independent Healthcare Education has assigned 1.0 contact hour (0.100 CEU) for continuing pharmacy education credits for participating in this activity.

    ACPE UAN: 0473-9999-16-008-H01-P
    Activity type: Knowledge-based

    Contact This Provider

For questions regarding the content of this activity, contact the accredited provider for this CME/CE activity noted above. For technical assistance, contact [email protected]


Instructions for Participation and Credit

There are no fees for participating in or receiving credit for this online educational activity. For information on applicability and acceptance of continuing education credit for this activity, please consult your professional licensing board.

This activity is designed to be completed within the time designated on the title page; physicians should claim only those credits that reflect the time actually spent in the activity. To successfully earn credit, participants must complete the activity online during the valid credit period that is noted on the title page. To receive AMA PRA Category 1 Credit™, you must receive a minimum score of 80% on the post-test.

Follow these steps to earn CME/CE credit*:

  1. Read the target audience, learning objectives, and author disclosures.
  2. Study the educational content online or printed out.
  3. Online, choose the best answer to each test question. To receive a certificate, you must receive a passing score as designated at the top of the test. In addition, you must complete the Activity Evaluation to provide feedback for future programming.

You may now view or print the certificate from your CME/CE Tracker. You may print the certificate but you cannot alter it. Credits will be tallied in your CME/CE Tracker and archived for 6 years; at any point within this time period you can print out the tally as well as the certificates from the CME/CE Tracker.

*The credit that you receive is based on your user profile.

CME / CE

Recognizing the Significance of Pseudomonas aeruginosa Resistance: Where Do We Stand Today?

Authors: Keith S. Kaye, MD, MPH; Keith A. Rodvold, PharmD, FCCP, FIDSAFaculty and Disclosures
THIS ACTIVITY HAS EXPIRED

CME / CE Released: 10/24/2016

Valid for credit through: 10/24/2017

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