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Amyloid PET Imaging: Appropriate Use Criteria

  • Authors: Keith A. Johnson, MD
  • CME Released: 5/30/2014
  • Valid for credit through: 5/30/2015
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Target Audience and Goal Statement

This activity is intended for neurologists, radiologists, psychiatrists, geriatric psychiatrists, and nuclear medicine physicians.

The goal of this activity is to summarize appropriate use criteria for amyloid positron-emission tomographic (PET) imaging in Alzheimer's disease and discuss clinical situations in which such imaging may be useful.

Upon completion of this activity, participants will be able to:

  1. Discuss the role and clinical utility of appropriate use criteria for amyloid imaging
  2. Describe the role of the dementia expert in the process of assessing patients with cognitive impairment
  3. Identify patient types and clinical circumstances in which amyloid PET is appropriately or inappropriately used


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Medscape, LLC, encourages Authors to identify investigational products or off-label uses of products regulated by the US Food and Drug Administration, at first mention and where appropriate in the content.


  • Keith A. Johnson

    Director of Molecular Imaging, Massachusetts General Hospital; Associate Professor of Radiology, Harvard Medical School, Boston, Massachusetts


    Disclosure: Keith A. Johnson, MD, has disclosed the following relevant financial relationships:
    Served as an advisor or consultant for: Siemens Healthcare Diagnostics Inc.; Genzyme Corporation; Piramal Healthcare
    Received grants for clinical research from: Avid Radiopharmaceuticals, Inc.; Lilly USA, LLC; Pfizer Inc; Elan Pharmaceuticals, Inc.; Ortho-McNeil-Janssen Pharmaceuticals, Inc.

    Dr Johnson does not intend to discuss off-label uses of drugs, mechanical devices, biologics, or diagnostics approved by the FDA for use in the United States.

    Dr Johnson does intend to discuss investigational drugs, mechanical devices, biologics, or diagnostics not approved by the FDA for use in the United States.


  • Ron Schaumburg, MA

    Scientific Director, Medscape, LLC


    Disclosure: Ron Schaumburg, MA, has disclosed no relevant financial relationships

  • Kristin M. Richardson

    Lead Scientific Director, Medscape, LLC


    Disclosure: Kristin M. Richardson has disclosed no relevant financial relationships.

CME Reviewer(s)

  • Nafeez Zawahir, MD

    CME Clinical Director, Medscape, LLC


    Disclosure: Nafeez Zawahir, MD, has disclosed no relevant financial relationships.

Accreditation Statements

    For Physicians

  • Medscape, LLC is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

    Medscape, LLC designates this enduring material for a maximum of 0.50 AMA PRA Category 1 Credit(s)™ . Physicians should claim only the credit commensurate with the extent of their participation in the activity.

    Medscape, LLC staff have disclosed that they have no relevant financial relationships.

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This activity is designed to be completed within the time designated on the title page; physicians should claim only those credits that reflect the time actually spent in the activity. To successfully earn credit, participants must complete the activity online during the valid credit period that is noted on the title page. To receive AMA PRA Category 1 Credit™, you must receive a minimum score of 70% on the post-test.

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Amyloid PET Imaging: Appropriate Use Criteria

Authors: Keith A. Johnson, MDFaculty and Disclosures

CME Released: 5/30/2014

Valid for credit through: 5/30/2015


Contents of This CME Activity

All sections of this activity are required for credit.

Section 1. Amyloid Imaging 101: Why, What, When, and for Whom

Dr Keith A. Johnson reviews the appropriate use criteria for amyloid imaging.
Keith A. Johnson, MD


Section 2. Frequently Asked Questions About Beta-Amyloid Imaging

Review the FAQs that healthcare professionals ask about beta-amyloid imaging.


Assess your clinical knowledge by completing this brief survey. Answering these questions again after the activity will allow you to see what you learned and to compare your answers with those of your peers.

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