This activity was developed for urologists, primary care physicians (PCPs), and related healthcare providers who assess and manage patients with BPH-LUTS and commonly co-occurring disorders, particularly erectile dysfunction.
Benign prostatic hyperplasia (BPH) is a pathologic diagnosis characterized primarily by proliferation of prostatic stromal and epithelial cells. When BPH is associated with lower urinary tract symptoms (LUTS; eg, urinary frequency, hesitancy, and intermittency; incomplete voiding; weak urine stream; nocturia; and urgency), BPH-LUTS becomes a clinical diagnosis.1 Highly prevalent and often underdiagnosed, BPH-LUTS is a chronic and progressive condition that greatly increases functional impairment, diminishes quality of life, and interferes with sexual function and other aspects of daily living.1-4 Further, patients with BPH-LUTS often have co-occurring conditions, including ED (BPH-LUTS+ED) in particular, as well as metabolic syndrome, cardiovascular abnormalities, and other morbidities that may challenge the management of this patient population.3,5-7
Multidimensional assessment of BPH-LUTS±ED is critical to recognition of the condition and is predicated primarily on a thorough patient evaluation that includes a focused history, physical exam, and minimal laboratory tests. At times, referral to a specialist is warranted, although many patients can be managed sufficiently in the primary care setting. As it largely guides treatment of patients with BPH-LUTS±ED, information about symptom severity and the degree of bother are critical to optimal therapy and patient outcomes. While watchful waiting is often used for patients with minimal symptoms and bother, Level 1 evidence supports currently available monotherapy and multidrug regimens to ameliorate urinary symptoms and slow disease progression in patients whose symptoms are more severe.8-10 As BPH-LUTS is a progressive condition, ongoing monitoring is warranted in this patient population. This educational activity is designed to enhance the clinician's understanding of the complex, interrelated nature of BPH-LUTS±ED, and best practices for initial and ongoing management.
1. Roehrborn CG. Int J Impot Res. 2008;20(suppl 3):S11-S18.
2. DeCastro J, Stone B. Am J Med. 2008;121(8 suppl 2):S27-S33.
3. McVary KT. BJU Int. 2006;97(suppl 2):S23-S28.
4. Rosenberg MT, et al. Int J Clin Pract. 2010;64:488-496.
5. Gacci M, et al. Eur Urol. 2011;60:809-825.
6. Johnson TV, et al. Urology. 2010;76:1317-1320.
7. McVary KT, et al. J Urol. 2011;185:1793-1803.
8. Greco KA, McVary KT. Int J Impot Res. 2008;20(suppl 3):S33-S43.
9. Hollingsworth JM, et al. J Urol. 2009;182:2410-2414.
10. McConnell JD, et al. N Engl J Med. 2003;349:2387-2398.
Upon completion of this activity, participants should be able to:
All faculty and staff involved in the planning or presentation of continuing education activities sponsored/provided by Purdue University College of Pharmacy are required to disclose to the audience any real or apparent commercial financial affiliations related to the content of the presentation or enduring material. Full disclosure of all commercial relationships must be made in writing to the audience prior to the activity.
This activity has been planned and implemented in accordance with the Essential Areas and Policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint sponsorship of Purdue University College of Pharmacy and Asante Communications LLC. Purdue University College of Pharmacy, an equal access/equal opportunity institution, is accredited by the ACCME to provide continuing medical education for physicians.
This CME activity is structured around consensus statements developed by a working group of experts with particular expertise in the multidimensional care of benign prostatic hyperplasia-lower urinary tract symptoms (BPH-LUTS) patients with or without erectile dysfunction (ED). Using a modified Delphi process, the BPH-LUTS Working Group has consolidated published evidence and expert clinical experience on critical issues pertaining to the phenomenology of BPH-LUTS±ED, assessment and diagnosis, treatment, ongoing management, and interdisciplinary care. Findings from the Delphi process informed the topics highlighted in this video roundtable CME activity.
Purdue University College of Pharmacy designates this enduring material for a maximum of 1.0 AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
For questions regarding the content of this activity, contact the accredited provider for this CME/CE activity noted above. For technical assistance, contact [email protected]
There are no fees for participating in or receiving credit for this online educational activity. For information on applicability
and acceptance of continuing education credit for this activity, please consult your professional licensing board.
This activity is designed to be completed within the time designated on the title page; physicians should claim only those
credits that reflect the time actually spent in the activity. To successfully earn credit, participants must complete the
activity online during the valid credit period that is noted on the title page. To receive AMA PRA Category 1 Credit™, you must receive a minimum score of 70% on the post-test.
Follow these steps to earn CME/CE credit*:
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CME Released: 9/17/2012
Valid for credit through: 9/17/2013
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