Rapid-Cycling Bipolar Disorder

Kupka RW, Luckenbaugh MA, Post RM, et al. Rapid and non-rapid cycling bipolar disorder: a meta-analysis of clinical studies. J Clin Psychiatry. 2003;64:1483-1494. Abstract
Dunner DL, Fieve RR. Clinical factors in lithium carbonate prophylaxis failure. Arch Gen Psychiatry. 1974;30:229-233. Abstract
American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders. 4th ed, text revision. Washington, DC: American Psychiatric Association; 2000.
Schneck CD, Miklowitz DJ, Calabrese JR, et al. Phenomenology of rapid-cycling bipolar disorder: data from the first 500 participants in the systematic treatment enhancement program. Am J Psychiatry. 2004;161:1902-1908. Abstract
Coryell W, Endicott J, Keller M. Rapidly cycling affective disorder. Arch Gen Psychiatry. 1992;49:126-131. Abstract
Koukopoulos A, Sani G, Koukopoulos AE, et al. Duration and stability of the rapid-cycling course: A long-term personal follow-up of 109 patients. J Affec Dis. 2003;73:75-85.
Ghaemi SN, Hsu DJ, Soldani F, et al. Antidepressants in bipolar disorder: the case for caution. Bipolar Disord. 2003;5:421-433. Abstract
Wehr TA, Sack DA, Rosenthal NE, Cowdry RW. Rapid cycling affective disorder: contributing factors and treatment responses in 51 patients. Am J Psychiatry. 1988;145:179-184. Abstract
Wolpert EA, Goldberg JF, Harrow M. Rapid cycling in unipolar and bipolar affective disorders. Am J Psychiatry. 1990;147:725-728. Abstract
Practice guideline for the treatment of patients with bipolar disorder (revision). Am J Psychiatry. 2002;159(4 suppl):1-50.
Calabrese JR, Shelton MD. Bowden CL, et al. Bipolar rapid cycling: focus on depression as its hallmark. J Clin Psychiatry. 2001;62(suppl 14):34-41. Abstract
Tondo L, Hennen J, Baldessarini RJ. Rapid-cycling bipolar disorder: effects of long-term treatments. Acta Psychiatr Scand. 2003;108:4-14. Abstract
Shelton MD III, Rapport DJ, Youngstrom EA, et al. Is rapid cycling a predictor of nonresponse to lithium? Program and abstracts of the 157th Annual Meeting of the American Psychiatric Association; New York, NY; May 1-6, 2004. Abstract 759.
Calabrese JR, Suppes T, Bowden CL, et al. A double-blind, placebo-controlled, prophylaxis study of lamotrigine in rapid cycling bipolar disorder. Lamictal 614 Study Group. J Clin Psychiatry. 2000;61:841-850. Abstract
Sanger TM, Tohen M, Vieta E, et al. Olanzapine in the acute treatment of bipolar I disorder with a history of rapid cycling. J Affect Disord. 2003;73:155-161. Abstract
Keck P, Corya S, Andersen SW, et al. Analysis of olanzapine/fluoxetine combination in the treatment of rapid-cycling bipolar depression (presentation). Program and abstracts of the 43rd Annual New Clinical Drug Evaluation Unit Meeting; Boca Raton, Florida; May 2003. Abstract I-100.
Vieta E. Calabrese J, McFadden W, et al. Quetiapine for the treatment of rapid-cycling bipolar depression. Program and abstracts of the European Stanley Foundation Conference on Bipolar Disorder; Aarhus, Denmark; September 24-26, 2004.
Suppes T, Ozcan ME, Carmody T. Response to clozapine of rapid cycling versus non-cycling patients with a history of mania. Bipolar Disord. 2004;6:329-332. Abstract
Grunze H, Amann B, Dittman S, et al. Clinical relevance and treatment possibilities of bipolar rapid cycling. Neuropsychobiology. 2002;45:20-26. Abstract
Pazzaglia PJ, Post RM, Ketter TA, et al. Preliminary controlled trial of nimodipine in ultra-rapid cycling affective dysregulation. Psychiatr Res. 1993;49:257-272.
Keck PE Jr., McElroy SL, Freeman MP, et al. Randomized, placebo-controlled trial of eicosopentanoic acid (EPA) in rapid cycling bipolar disorder. Program and abstracts of the 5th International Conference on Bipolar Disorder; Pittsburgh, Pennsylvania; June 12-14, 2003.
Satterfield JM. Adjunctive cognitive-behavioral therapy for rapid-cycling bipolar disorder: an empirical case study. Psychiatry. 1999;62:357-369. Abstract

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Introduction

Rapid cycling is a descriptive term referring to the presence of 4 or more discrete affective episodes in a 1-year period. For patients, it may bring frequent hospitalizations and severe life disruptions. For their physicians, rapid cycling often means frustrating attempts to manage a phase of bipolar illness that can render traditional pharmacotherapies ineffective. However, in recent years, investigators have begun to better understand the clinical importance of this condition, and key questions about its nature and management have come into focus. The result is that clinicians can now have a clearer understanding of the phenomenology of rapid cycling and greater confidence in their ability to treat it.

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The Phenomenology of Rapid Cycling

References

Rapid-Cycling Bipolar Disorder: Emerging Treatments and Enduring Controversies

Introduction

Table of Contents

References

Faculty and Disclosures

Rapid-Cycling Bipolar Disorder: Emerging Treatments and Enduring Controversies

Introduction

Table of Contents