The importance of technology in playing a definitive role in improving the delivery of health care is evolving rapidly. As a direct result of the exponential growth in computational power, machine learning algorithms are finding growing use in medical science, driving advances in the development of artificial intelligence to support clinicians in complex tasks. Big data and a whole host of technological advances are set to revolutionize medicine in the future. In this series we’ll explore these technologies, their potential for transforming clinical practice, and the challenges along the way, with experts, Dr Pearse Keane, Professor Philippe Cattin, and Professor Tjalf Ziemssen.