Rare Hematological Disorders

Clinical Advances in Rare Hematological Disorders

Acquired hemophilia A (AHA) and congenital thrombotic thrombocytopenic purpura (cTTP) are both rare hematological disorders.

With an incidence of ~ 1.5 per million, most physicians will rarely see a patient with AHA. Given its rarity and the large range of often nonspecific presenting bleeds, delayed and missed diagnoses are common. Availability and familiarity of treatment options is also an ongoing problem.

Similarly, since cTTP is an ultra-rare thrombomicroangiopathy that can present at any age, identification of the condition is challenging and delayed and misdiagnoses occur frequently. Furthermore, the standard of care has been unchanged for almost 30 years and therefore awareness of emerging treatments is imperative.

This Clinical Advances educational initiative will include discussions with top faculty in their respective fields to educate and inform on identification, diagnosis, and treatment to better improve the management and care of their patients who present with these rare disorders.