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Clinical Advances in

Pertussis Disease: Solutions for All Ages

Pertussis, or whooping cough, is a highly contagious lower respiratory tract infection caused by Bordetella pertussis and represents an important cause of infant death worldwide. Despite high vaccination rates in some countries, the incidence of pertussis continues to rise in persons of all ages and presents an important global public health concern. Increased control of pertussis depends, in part, on implementing strategies to maximize the effectiveness of available vaccines to protect those at risk of infection.

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Polling Question

Which of the following factors is the most important contributor to the resurgence of pertussis disease?
Vaccine coverage
Vaccine failure
More sensitive biological diagnosis
Micro-organism changes
There is no resurgence of pertussis disease

Related Resources

Downloadable Slide Kit

Pertussis: Prevention Through Vaccination


Pertussis: Diagnosis and Treatment


Clinical Articles

Safety of Pertussis Vaccination in Pregnant Women in UK: Observational Study  

Epidemic Pertussis in 2012 - The Resurgence of a Vaccine-Preventable Disease  

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Steering Committee

Stanley A. Plotkin, MD

Steering Committee Chair

Professor Emeritus, University of Pennsylvania, The Wistar Institute, Philadelphia, Pennsylvania, United States

Nicole Guiso-Maclouf, PhD

Former Head, Research Unit, Institut Pasteur; Director, National Reference Centres for Pertussis and Diphtheria, Paris, France

Terry M. Nolan, MBBS, PhD

Head, Melbourne School of Population and Global Health, University of Melbourne, Melbourne, Victoria, Australia