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Introduction

Epidemiological and clinical data linking low-density lipoprotein cholesterol (LDL-C) with cardiovascular (CV) disease are well established. Numerous primary and secondary prevention trials have demonstrated that reduction in LDL-C levels leads to a significant decrease in cardiovascular event rates. However, patients may not be able to achieve target LDL-C goals and remain at a substantial risk for CV events. The Clinical Advances in Cardiovascular Disease Risk Reduction curriculum is designed to provide education on the latest clinical advances in effective LDL-C-lowering strategies.

Activities

Steering Committee

Steering Committee Members
  • Michael H. Davidson, MDMichael H. Davidson, MD
    Clinical Professor of Medicine; Director, Preventive Cardiology, Pritzker School of Medicine,
    The University of Chicago,
    Chicago, Illinois
  • Robert H. Eckel, MDRobert H. Eckel, MD
    Professor of Medicine, University of Colorado Anschutz Medical Campus; Director, Lipid Clinic, University of Colorado Hospital, Aurora, Colorado
  • Darren K. McGuire, MD, MHScDarren K. McGuire, MD, MHSc
    Associate Professor, University
    of Texas Southwestern Medical
    Center at Dallas
  • Stephen J. Nicholls, MBBS, PhD, FRACPStephen J. Nicholls, MBBS, PhD, FRACP
    Professor of Cardiology, SAHMRI Heart Foundation Heart Disease Theme Leader, South Australian Health & Medical Research Institute, Adelaide, Australia
Supported by an independent educational
grant from Merck & Co.
Polling Question

Which of the following statements best describes your opinion regarding the 2013 ACC/AHA lipid guidelines in managing high-risk patients?
I agree with high-efficacy statins and no recommended therapeutic goal
I prefer the Canadian guidelines: ≥50% LDL-C lowering with statin therapy
I prefer to continue to follow the ATP III guidelines
I prefer the AACE guidelines: aggressive LDL-C and non-HDL-C targets
I am confused about the new guidelines

Related Resources

Downloadable Slide Kit

Disclosures

Steering Committee
Michael H. Davidson, MD

Michael H. Davidson, MD, has disclosed the following relevant financial relationships:
Served as an advisor or consultant for: Amgen Inc.; AstraZeneca Pharmaceuticals LP; Merck & Co., Inc.; Sanofi
Owns stock, stock options, or bonds from: Omthera Pharmaceuticals, Inc.

Robert H. Eckel, MD

Robert H. Eckel, MD, has disclosed the following relevant financial relationships:
Served as an advisor or consultant for: Amylin Pharmaceuticals, Inc.; Lilly USA, LLC; Novo Nordisk; Sanofi

Darren K. McGuire, MD, MHSc

Darren K. McGuire, MD, MHSc, has disclosed the following relevant financial relationships:
Served as an advisor or consultant for: Roche; Daiichi Sankyo, Inc.; Genentech, Inc.; Sanofi, Novo Nordisk; Pfizer Inc; Regeneron Pharmaceuticals, Inc.
Received grants for clinical research from: Roche; Genentech, Inc.; Lilly USA, LLC; Daiichi Sankyo; Novo Nordisk; Bristol-Myers Squibb Company; AstraZeneca Pharmaceuticals LP; Boehringer Ingelheim Pharmaceuticals, Inc.; Takeda Pharmaceuticals North America, Inc.; Orexigen Therapeutics, Inc.

Stephen J. Nicholls, MBBS, PhD, FRACP

Stephen J. Nicholls, MBBS, PhD, FRACP, has disclosed the following relevant financial relationships:
Served as an advisor or consultant for: Boehringer Ingelheim Pharmaceuticals, Inc.; CSL Behring; Esperion Therapeutics, Inc.; Merck & Co., Inc.; Omthera Pharmaceuticals, Inc.; Roche; Takeda Pharmaceuticals North America, Inc.
Received grants for clinical research from: Anthera Pharmaceuticals; AstraZeneca Pharmaceuticals LP; Eli Lilly and Company; LipoScience Inc.; Novartis Pharmaceuticals Corporation; Resverlogix Corp; Roche