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Clinical Advances in

ANCA-Associated Vasculitis

Antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) is a potentially fatal autoimmune condition characterized by damage to, and inflammation of, small blood vessels commonly in the kidneys, respiratory tract or the skin. Current treatment for AAV consists of various therapies that have not been studied in placebo-controlled trials. Novel agents targeting Complement 5a have the potential to revolutionize the treatment of AAV. The aim of this curriculum is to educate clinicians on the most recent advances in the management of patients with AAV.

Supported by an independent educational grant from

Vifor Pharma


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Related Resources

Downloadable Slide Kit

Clinical Advances in ANCA-Associated Vasculitis


Clinical Reference

ANCA associated vasculitis: the journey to complement-targeted therapies.  

Comparisons of guidelines and recommendations on managing antineutrophil cytoplasmic antibody-associated vasculitis  

Revised 2017 international consensus on testing of ANCAs in granulomatosis with polyangiitis and microscopic polyangiitis  

ANCA-Associated Vasculitis: Core Curriculum 2020.  

Randomized trial of C5a receptor inhibitor avacopan in ANCA-associated vasculitis  

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Steering Committee

David Jayne, MD, FMedSci

Steering Committee Chair

Professor of Clinical Autoimmunity
University of Cambridge
Cambridge, United Kingdom

Y.K.O. Teng, MD, PhD

Department of Internal Medicine, Nephrology
Expert Center for Lupus- Vasculitis- and Complement-mediated Systemic Autoimmune Diseases
Leiden University Medical Center
Leiden, The Netherlands

Benjamin Terrier, MD, PhD

Professor of Medicine
Cochin Hospital
Paris, France

Vladamir Tesar, MD, PhD, MBA, FERA, FASN

General University Hospital
Charles University
Prague, Czech Republic

Augusto Vaglio, MD, PhD

Associate Professor of Nephrology
University of Florence
Nephrology Unit
Meyer Children’s Hospital
Florence, Italy