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CME/CE Test

Depicting LAG3: Exploring a New Target in Metastatic Melanoma

  1. What feature of LAG3 is necessary for its ability to exert a negative effect on T-cell function?
    Affinity with MHC Class II
    Intracellular KIEELE motif
    Proline-rich loop at the D1 domain
    Structural homology with CD4