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      Friday, March 31, 2023
      News & Perspective Drugs & Diseases CME & Education Academy Video Decision Point
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      CME/CE Test

      Pathologies and the Use of Cerebrospinal-Fluid-Based Biomarkers in Alzheimer Disease

      1. What biomarkers are currently FDA approved for the diagnosis of AD?
        Aβ40 and neurofilament light
        Aβ42/40 and Aβ42/tau
        Tau and neurofilament light
        Neurofilament light
      2. Which APOE variant is associated with AD?
        1
        2
        3
        4
      3. Biomarkers for AD are judged by their concordance to what?
        Plasma markers
        Magnetic resonance imaging (MRI)
        Amyloid positron emission tomography (PET)
        Clinical diagnosis
      4. Which biomarkers for AD have been found to be different between racial groups?
        Aβ42, Aβ40, tau, neurofilament light
        Aβ40, tau, neurofilament light
        Tau and neurofilament light only
        Neurofilament light only
      5. Why are AD CSF biomarkers often used in a ratio?
        To negate individual differences
        To account for racial disparities
        To identify other neurological diseases
        Ratios are no more useful than individual markers alone
       
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