What Factors Compound the Risk for Gout in Those Genetically Predisposed?

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1. You are a member of the healthcare team for a 58-year-old man whose brother was just diagnosed with gout, and he wants to know about his risk for gout. What can you tell him about risk factors for gout?
   Sex does not affect the risk for gout
   Black race is associated with a higher risk for gout
   About half of adults with gout have a family history of gout
   The risk for gout is increased about 7-fold among adults with a family history of gout
2. What does the current study find regarding family history and the risk for incident gout?
   Having a first-degree relative with gout increased the risk for incident gout between 2- and 3-fold
   Having a first-degree relative with gout increased the risk for incident gout between 7- and 8-fold
   There was no interaction between overweight/obesity and family history as risk factors for gout
   Alcohol consumption was not a significant risk factor for gout