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Evaluating Evolving Approaches to Treating Thrombosis in Cancer: From Concept to Clinic

  1. Which of the following best reflects an unmet need with current cancer-associated thrombosis (CAT) treatment?
    Direct oral anticoagulants (DOACs) have a poor safety profile leading to underuse
    Bleeding is a frequent side effect with current anticoagulant options
    Current options do not allow for individualization of treatment
    With current treatment options, there isn’t the inability to transition between therapies when needed
  2. Evidence for the use of factor XI inhibition in the treatment of CAT includes which of the following?
    Factor XI is more important for thrombosis than for hemostasis
    Factor XI inhibitors may spare thrombosis and offer better safety than current anticoagulants
    The hemostasis and thrombosis loops act in a closely intertwined loop