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CME/CE Test

What is the Impact of Ischemic Heart Disease on Maternal Morbidity and Mortality?

  1. You are a member of the healthcare team for a 34-year-old woman with isolated ischemic heart disease (IHD) who is considering pregnancy. According to the retrospective study using the 2015-2018 Nationwide Readmissions Database by Denoble and colleagues, which of the following statements about adverse pregnancy outcomes of women with IHD compared with women with and women without a cardiac diagnosis is correct?
    In unadjusted analyses, adverse outcomes were similar among patients with IHD alone vs patients with modified World Health Organization (mWHO) class I to II disease
    After adjustment, patients with IHD alone had significantly higher risk for severe maternal morbidity (SMM) or death than patients with mWHO I to II cardiac diseases
    After adjustment, patients with IHD alone had higher risk for SMM or death (adjusted relative risk [aRR] 1.51 [95% CI: 1.19, 1.92]) than patients without cardiac disease
    After adjustment, patients with IHD alone had higher risk for preterm birth than patients without cardiac disease
  2. According to the retrospective study using the 2015-2018 Nationwide Readmissions Database by Denoble and colleagues, which of the following statements about clinical implications of adverse pregnancy outcomes of women with IHD compared with women with and women without a cardiac diagnosis is correct?
    Pregnancy is contraindicated in women with preexisting isolated IHD
    The findings may be useful in counseling patients and could help further refine mWHO classification of maternal cardiovascular (CV) risk
    Clinicians should reassure women with preexisting isolated IHD that pregnancy is completely safe
    All pregnant women with IHD need intensive CV monitoring and supervision throughout pregnancy