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Exploring the Significance of Cytomegalovirus: From Diagnosis to Risk Reduction Strategies

  1. Approximately what percentage (range) of women in North America are seropositive for CMV in their reproductive age?
    20% to < 40%
    40% to < 60%
    60% to < 80%
    80% to < 100%
  2. Per ACOG and SMFM guidelines, routine serologic screening of pregnant patients for CMV is not recommended. However, a 2-month pregnant patient with mild flu-like symptoms presents in your office because she is concerned about exposure to CMV since she has a toddler in daycare.
    Which of the following is more accurate to detect a primary CMV maternal infection during pregnancy?
    IFN-γ release assay
    Urine virology testing by PCR
    IgM as measured by ELISA
    IgG avidity index
  3. What is the most frequent sequela in infants with symptomatic congenital CMV?
    Intellectual disability
    Sensorineural hearing loss
    Cerebral palsy