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CME/CE Test

Is the COVID-19 Vaccine Safe for Pregnant Women?

To receive AMA PRA Category 1 Credit™, you must receive a minimum score of 75% on the post-test.

  1. You are a member of the healthcare team advising a large obstetrics practice regarding COVID-19 vaccination in pregnancy. According to the CANVAS network observational cohort study by Sadarangani and colleagues, which of the following statements about the frequency and nature of significant health events among pregnant female persons after COVID-19 vaccination compared with unvaccinated pregnant control participants and vaccinated nonpregnant individuals is correct?
    Pregnant vaccinated vs unvaccinated female persons had increased odds for a significant health event within 7 days after BNT162b2 dose 2
    Serious health events occurred in 2% of pregnant vaccinated women, significantly higher than in the other 2 groups
    For pregnant vs nonpregnant vaccinated women, odds of a significant health event were lower after dose 1 (adjusted odds ratio [aOR] 0.63) and dose 2 (aOR 0.62) of any messenger RNA (mRNA) vaccine
    Miscarriage and stillbirth were significantly more common in vaccinated women
  2. According to the CANVAS network observational cohort study by Sadarangani and colleagues, which of the following statements about clinical and public health implications of the frequency and nature of significant health events among pregnant female persons after COVID-19 vaccination compared with unvaccinated pregnant control participants and vaccinated nonpregnant individuals is correct?
    These data can appropriately inform pregnant women regarding reactogenicity of COVID-19 vaccines during pregnancy
    The mRNA-1273 vaccine should be contraindicated during pregnancy
    COVID-19 vaccination should be deferred until after delivery
    The findings likely will convince all pregnant women to get vaccinated