Taking Action in Heart Failure: The Universal Language of Success

Which of the following measurements is used to classify or characterize heart failure (HF) type?

According to European, US, and Canadian guidelines, which of the following agents(s) are considered part of the foundational drug classes for HFrEF treatment?

Cristina is a 63-year old woman with HFrEF, coronary artery disease, hypertension, dyslipidemia, type 2 diabetes, obesity, and depression. She is currently taking simvastatin 20 mg once daily for her dyslipidemia. Her low-density lipoprotein-cholesterol (LDL-C) is 133 mg/dL (3.44 mmol/L) (goal < 55 mg/dL [< 1.4 mmol/L]).

According to current guidelines, which of the following adjustments should be made first to help Cristina meet her LDL-C goal?