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Hypertension Case Studies With Single-Pill Combinations

  1. In 2018, the ESC and ESH published their guidelines for the management of systemic arterial hypertension
    According to the 2018 European Society of Cardiology (ESC) and European Society of Hypertension (ESH) guidelines for the management of arterial hypertension, which of the following blood pressure ranges (mmHg) is categorized as grade 1 hypertension, with an indication for immediate drug treatment in high- or very high-risk patients?
    Systolic blood pressure (SBP) 130 to 139; diastolic blood pressure (DBP) 85 to 89
    SBP 130 to 139; DBP 85 to 89
    SBP 140 to 159; DBP 90 to 99
    SBP 160 to 179; DBP 100 to 109
  2. A 58-year-old man presents in your clinic with an office BP of 157/88 mmHg, a BMI of 34 kg/m2, normal cardiovascular exam, normal electrocardiogram, normal renal function, and mild concentric hypertrophy on echocardiogram with borderline left atrial enlargement. His fasting glucose is 6.6 mmol/L. His low-density lipoprotein level is 3.8 mmol/L and his triglyceride level is 2.3 mmol/L.
    According to the 2018 ESC and ESH Guidelines for the management of arterial hypertension, what is your initial choice of drug treatment in this patient?
    Dual combination of a renin-angiotensin-system (RAS) blocker and calcium channel blocker (CCB) as a single pill
    Dual combination of RAS blocker and diuretic as a single pill
    Triple combination of RAS blocker, CCB, and diuretic
    Triple combination of RAS blocker, CCB, and diuretic, along with once-daily spironolactone