What Does the Evidence Reveal about Insomnia Treatment?

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1. You are a member of the healthcare team seeing a 57-year-old woman who complains of 2 months of insomnia. Sleep hygiene interventions have not worked, and she requests a Z drug for insomnia. On the basis of the previous review by Treves and colleagues, what can you tell her regarding the safety of Z drugs?
   They promote higher risks for both falls and fracture
   They promote higher risks for falls, but not fracture
   They promote higher risks for fracture, but not falls
   They promote higher risks for falls only among patients with proven insomnia
2. Which one of the following drugs was supported by the best available evidence for the management of insomnia in the current study by de Crescenzo and colleagues?
   Mirtazapine and melatonin
   Triazolam and zolpidem
   Trazodone and doxepin
   Eszoplicone and lemborexant