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Return to Activity: Is Nonalcoholic Fatty Liver Disease Associated With Atherosclerotic Cardiovascular Disease?

CME/CE Test

Is Nonalcoholic Fatty Liver Disease Associated With Atherosclerotic Cardiovascular Disease?

You are a member of the health care team evaluating a 56-year-old man for atherosclerotic cardiovascular disease (ASCVD) risk. On the basis of the American Heart Association (AHA) scientific statement by Duell and colleagues, which one of the following statements about nonalcoholic fatty liver disease (NAFLD) diagnostic and screening strategies, course, and association with ASCVD is correct?

Aspartate aminotransferase (AST) and alanine aminotransferase (ALT) are useful for diagnosing NAFLD and nonalcoholic steatohepatitis (NASH)

Liver biopsy is the gold standard for diagnosing NAFLD and NASH, but it is expensive and may cause complications

Presence of NAFLD is associated with increased ASCVD risk solely because of its association with ASCVD risk factors

Hepatocellular carcinoma is the leading cause of death in patients with NAFLD
According to the AHA scientific statement by Duell and colleagues, which one of the following statements about potential interventions for NAFLD is correct?

A key intervention is lifestyle modification, including weight loss, increased physical activity, dietary modification, and alcohol avoidance

GLP-1 receptor agonists completely reverse NAFLD in most patients

5% to 10% body weight loss is insufficient to reverse hepatic steatosis

The drug pipeline for NAFLD has many safe, highly effective candidates