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Ask the Experts About Depression, Bipolar Disorder, and Schizophrenia

Ask the Experts About Depression, Bipolar Disorder, and Schizophrenia

 
 
  • Smoking and Schizophrenia What evidence-based treatment improves insight? In what phase of the illness is such intervention best? What undesirable clinical effects can insight have?
  • Insight and Schizophrenia What evidence-based treatment improves insight? In what phase of the illness is such intervention best? What undesirable clinical effects can insight have?
  • State-of-the-art Treatment for Negative Symptoms of Schizophrenia What are primary negative symptoms? How can you treat them? What are secondary negative symptoms and what 3 factors are responsible for them? How can you treat secondary negative symptoms?
  • Lithium and Hair Loss What can you do if your patient's thyroid test results are normal, but she is losing her hair? Why? If that option does not work, what other choices do you have?
  • Antipsychotics and Diabetes Which antipsychotics have the best metabolic profile? What should you do if your patient develops new-onset diabetes after taking antipsychotics? How can you best manage diabetes?
  • Antidepressant Withdrawl Mania as a Predictor of Bipolarity What is antidepressant withdrawal mania? What medications may be associated with this phenomenon and why? Does antidepressant withdrawal mania predict bipolarity?
  • The Effectiveness of ECT for Bipolar Disorder How effective is ECT for bipolar depression, depression with a switch into mania, refractory mania, and maintenance? For what 2 types of patients should it be considered a first-line treatment?
  • The Meaning of the Term "Bipolar Disorder" What differentiates bipolar from unipolar depression? What factors are relevant when considering antidepressants?
  • Atypical Antipsychotics and Bipolar Disorder Are olanzapine, quetiapine, ziprasidone, aripiprazole, and risperidone mood stabilizers? For how long can these atypical antipsychotics prevent relapses? When are relapses most likely to occur?
  • Distinguishing Bipolar From Unipolar Depression How can you recognize the depressed patient who is at increased risk for development of bipolar disorder? Here are some practical tips.
  • Antidepressants in the Pipeline What drugs act as agonists at the neurokinin (NK) level? How are they useful? When might they be approved by the FDA?
  • Sex and Antidepressants How often do SSRIs cause sexual dysfunction? When reducing the dosage does not help, what can you do? What options are best for which kinds of patients?
  • Bipolar Depression Why is it seemingly more difficult to treat bipolar depression than bipolar mania? Why does it seem so hard to get the FDA to approve medications for bipolar depression?
  • Managing the Side Effects of Clozapine What are the potential side effects of clozapine? Why? What pharamacologic and nonpharmacologic solutions can you offer your patients?
  • New Methods for the Administration of Psychiatric Medication How has the pharmacokinetic profile of some pills improved? What old drugs may be reformulated for lingual or nasal administration? What new techniques minimize metabolism by liver enzymes?
  • The New "Blue Light" Intervention for Seasonal Affective Disorder (SAD) How does light therapy work? What are its strengths and weaknesses? What 2 promising alternatives affect the circadian systems that mediate response to bright full-spectrum light?
  • What Is the Latest Scoop on Typical vs Atypical Antipsychotics? Find out about 2 major studies as well as 4 reasons why atypical (second-generation) antipsychotics might be better than typical (first-generation) antipsychotics for bipolar disorder.
  • Clozapine in Schizophrenia How many patients do not respond adequately to antipsychoptics? When should clozapine be used to treat them? What is an adequate dose? What should you do if a patient does not respond to that dose?
  • Suicide and Bipolar Disorder Who is more likely to attempt suicide: a person with bipolar I or bipolar II? Who is more likely to succeed: a person with bipolar vs unipolar mood disorder? Why do the data seem puzzling at first?
  • New Medications Which antidepressant is likely to come to market next? What 5HT1A, M1/M2, NK1, NK2, and other agonists are waiting in the wings? What triple reuptake inhibitors may be here in 2010?