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Nurses Clinical Briefs

  • A new analysis suggests that a polygenic score can help determine the best drug regimens for young Black patients with AML who often face worse outcomes than White patients.
    This Test May Guide AML Therapy for Black Pediatric Patients

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  • A new analysis found that patients with multiple myeloma receiving standard therapies have much worse outcomes compared with those treated in clinical trials.
    In Real World, Patients With Myeloma Have Worse Outcomes

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  • Unsatisfactory fecal immunochemical tests often stem from inadequate or old specimens, incomplete labeling, or broken/leaking containers, and they may leave many patients unscreened.
    1 in 10 Stool-Based CRC Tests Can't Be Processed

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  • GLP-1 agonists like semaglutide can help patients with obesity lose weight -- if they can get the medications.
    Prescribing GLP-1 Agonists

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  • The Amulet and Watchman FLX devices for left atrial appendage closure produced equivalent results, with about half of patients having residual patency of the appendage at 13 months, a study shows.
    Amulet and Watchman Equal for Left Atrial Appendage Closure

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  • The Home Test to Treat program is virtual and offers at-home rapid tests, telehealth sessions, and at-home treatments to people nationwide.
    Federal Program Offers Free COVID, Flu At-Home Tests, Rx

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  • "Tape strips can provide important clues to when and which drugs to use in HS in patients with both early and late disease, which can change clinical practice."
    Tape Strips Detect Hidradenitis Suppurativa Biomarkers

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  • Women aged 65-70 years old are often offered the option of skipping radiation after lumpectomy for hormone receptor–positive early-stage breast cancer and moving straight to endocrine therapy.
    Can Younger Postmenopausal Women With BC Skip Radiation?

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  • Bullous pemphigoid has high morbidity and mortality, especially in people with comorbidities common to older adults, yet no Food and Drug Administration–approved therapies for BP exist.
    Combined Rituximab + Omalizumab Promising for Refractory BP

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  • The drive may become stuck or hard to turn, raising the possibility that the patient may not receive adequate hemodynamic support or gas exchange.
    FDA Class I Recall for Getinge Cardiohelp Emergency Drive

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  • If approved, the ADC would join sacituzumab govitecan (Trodelvy, Gilead) as agents that target trophoblast cell-surface antigen-2 (Trop-2), which is universally expressed in breast cancer.
    Trop-2 Drug Conjugate May Trump Chemo in HR+, HER2- BRCA

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  • Elagolix sodium, an oral short-acting nonpeptide gonadotropin-releasing hormone antagonist has been approved by the FDA at a dose of 300 mg twice daily with add-back therapy for up to 24 months.
    Elagolix Curbs Heavy Bleeding Linked to Uterine Leiomyomas

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  • New data from the POSITIVE trial show the efficacy and short-term safety of fertility preservation and assisted reproductive technology (ART) for young women with HR-positive breast cancer.
    Patients With HR-Positive Breast Cancer Can Safely Use ART

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  • One of the treatments, exa-cel, marks the first to use the gene-editing tool CRISPR.
    FDA OKs Two Gene-Editing Therapies for Sickle Cell Disease

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  • Talk about bloodlines: In the Brodsky family, the field of hematology tied father to son. Now, a grandson is heading into the "family business."
    Hematology Is in the Brodsky Family's Blood

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  • Long-term data showed negligible differences in mortality among hypertensive adults treated with thiazide-type diuretics, calcium channel blockers, or angiotensin-converting enzyme inhibitors.
    Antihypertensives Show Similar Long-Term Mortality Rates

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  • Patients with migraine are less likely to respond to the new CGRP monoclonal antibody preventive treatments, if they have certain psychiatric disorders, new research shows.
    Psych Disorders May Reduce Response to CGRPs for Migraine

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  • Triptans, ergots, and antiemetics were ranked as the top three most effective acute migraine medications in an analysis of 10.8 million users' self-reported records.
    Which Migraine Medications Are Most Effective?

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  • The percentage of patients with a U09.9 diagnostic code in the year after a SARS-CoV-2 infection ranged from less than 4% in one region to more than 24% in another
    Wide Regional Variation in Diagnosis of Long COVID

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  • Tandem Diabetes Care's t:slim X2 and Beta Bionics' iLet will incorporate Dexcom G7, its latest continuous glucose monitoring system.
    Two Automated Insulin Delivery Systems Upgrade

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    Recent evidence holds implications for the management of type 2 diabetes.
    0.50 CME/CEMIN 0.50 ABIM MOCMIN 0.50 CEMIN 0.50 CEMIN 0.50 CEMIN

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    Did you know that recent studies show diverse skin tones are depicted in less than 5% of medical textbooks and publications?
    Best Practices for Enhancing Diversity in Dermatology Imagery
    0.25 CME/CEMIN 0.25 ABIM MOCMIN 0.25 CEMIN 0.25 CEMIN 0.25 CEMIN

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    A new study highlights which components of lipid profile variability are most important in predicting the risk for Alzheimer’s disease.
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    What's new in family medicine? UTI symptoms, TSH levels, and eating disorders.
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    What are the latest clinical considerations for COVID-19 vaccination and hepatitis C therapy?
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    New research reveals associations between growth hormones and Type 2 Diabetes (T2D) and long-term effects of antenatal corticosteroids.
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    A new randomized, placebo-controlled trial answers some questions while creating others.
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    Learn about recent findings in acetaminophen poisoning treatment guidelines, diet-related gut inflammation, and autism-linked self-harm.
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    Learn about recent findings in sexual HIV transmission and long COVID treatment research.
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    A study evaluates race/ethnicity, household income, and health insurance status as variables in the prevalence and severity of food allergy.
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    A new study compares rates of suicide-related behaviors based on sexual orientation.
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    A new study sheds light on how the COVID-19 pandemic affected the use of lysergic acid diethylamide and other psychedelic drugs.
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    A new study examines the prevalence of Crohn disease in a large cohort of adolescents with hidradenitis suppurativa.
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    What does the latest research on brain health show?
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    Read this week’s most popular articles on infectious diseases: Viral hepatitis and new findings on gut bacteria.
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    A new study assesses drugs with potential depressive symptom side effects among adults with depression.
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    New data provide powerful evidence for clinicians caring for young children.
    Are COVID-19 Vaccines Safe for Children Younger Than 5 Years?
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    A large cohort study suggests that transplantation of kidneys from donors with active or resolved COVID-19 is safe in the medium-term.
    Does COVID-19 Affect Donor Kidney Outcomes?
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    A new study examines the effect of alcohol on neural network activity to help promote salutary effects on the cardiovascular system.
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    Learn about new findings in hearing loss, brain disorders, and type 2 diabetes.
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