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Gynecologic Cancer Learning Center Clinical Briefs

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    Clinicians should emphasize the importance of timely human papillomavirus vaccination to ensure maximum effectiveness, NHANES data suggest.
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    Risk assessments before gynecologic cancer surgery might be tailored using cancer-specific malnutrition criteria, an analysis suggests.
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  • 10.25 90.25 20.25 30.25 80.25
    A Review of the Data 12 Years After Vaccine Introduction.
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  • 10.25 90.25 20.25
    Obesity raises colon, rectal, and liver cancer risk partly in a sex-dependent manner, mandating cancer risk evaluation in such patients.
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  • 10.25 90.25 20.25 30.25 80.25
    Breastfeeding was linked to lower maternal CVD risk in a large meta-analysis, mandating strategies to promote and facilitate breastfeeding.
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  • 10.25 90.25 20.25 30.25
    Cervical cancer/CIN3 incidence in young women fell substantially after the introduction of England's HPV immunization program.
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    As HPV-16/18 infection is linked to increased risk for preterm birth, HPV vaccination may reduce preterm birth and associated burden.
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  • US cancer deaths continue to fall overall and for many common cancers in both men and women, especially NSCLC and melanoma.

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    As ovarian cancer screening did not reduce ovarian/tubal cancer deaths in a large trial, general population screening cannot be recommended.
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  • When choosing surgery to prevent ovarian cancer, BRCA carriers consider cancer risk, menopause, and other factors.

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  • Pregnancy after breast cancer in women with germline BRCA mutations is safe without affecting prognosis and has favorable fetal outcomes.

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    Women with cervical cancer have an increased risk for inpatient care for iatrogenic and other injuries during workup, but these are rare.
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    The quadrivalent HPV vaccination was associated with a substantially reduced risk for invasive cervical cancer at the population level among Swedish girls and women aged 10 to 30 years.
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  • 10.25 90.25 20.25
    For cervical cancer screening, primary HPV testing is preferred, starting at age 25 and repeated every 5 years, based on updated American Cancer Society guidelines.
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  • 10.25 90.25 20.25
    As many elderly persons are screened for cancer after age limits, interventions to reduce overscreening are needed to lower patient harms and costs and to increase healthcare efficiency.
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    For the first time ever, a saliva screening test detected an occult HPV-driven oropharyngeal squamous cell carcinoma, suggesting these tests might prove useful for oropharyngeal cancer screening.
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  • 10.25 90.25 20.25
    Routine cervical screening every 3 years prevents 83% of nonlocalized cancers, with no added benefit of screening more often; increased coverage is needed to further lower cervical cancer incidence.
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  • 10.25 90.25 20.25 30.25
    Use of powder in the genital area was not significantly linked to incident ovarian cancer, but this analysis of pooled data from 4 US cohorts may have lacked power to detect a small increase in risk.
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  • 10.25 90.25 20.25 30.25
    Among cancer survivors, half drink alcohol, one-third drink more than moderately, and one-fifth binge drink, mandating public health strategies to reduce alcohol intake in this population.
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  • 10.25 90.25 20.25
    More than half of bimanual pelvic exams and almost 72% of Pap tests in women aged 15 to 20 years were potentially unnecessary, exposing women to preventable harms and suggesting lack of guidelines compliance.
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