Sepsis Resource Center Clinical Briefs

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  Does Time to Positivity Predict Mortality in Enterococcal Bloodstream Infections?
  Medscape Education Clinical Briefs September 27, 2021
  A new study finds that time to positivity of enterococcal cultures in bloodstream infections is not independently linked to mortality risk.
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  What Impact Does Convalescent Plasma Have on Blood Cancers and COVID-19?
  Medscape Education Clinical Briefs July 30, 2021
  Convalescent plasma offers potential survival benefit to patients with hematologic cancers and COVID-19, a retrospective cohort study shows.
  
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  Are Corticosteroid Bursts in Children Really Harmless?
  Medscape Education Clinical Briefs June 11, 2021
  Steroid bursts are linked to 1.4- to 2.2-fold increased risk for severe adverse events in children within the first month after initiation.
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• Low-Dose Steroids and Serious Infection Risk in RA Patients
  Medscape Education Clinical Briefs December 11, 2020
  New study suggests even low-dose glucocorticoids can raise risk for infection among patients with rheumatoid arthritis.
  
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  How Do We Differentiate Between COVID and MIS-C in Children?
  Medscape Education Clinical Briefs October 29, 2020
  MIS-C and COVID-19 are different SARS-CoV-2 diseases in children, distinguished by cytokine panels and peripheral blood smears.
  
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  Is There Much Risk Associated With Steroid Use?
  Medscape Education Clinical Briefs August 14, 2020
  New study details potential serious harm associated with oral corticosteroid bursts.
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  How Big a Problem Is Misdiagnosis in Medicine?
  Medscape Education Clinical Briefs July 02, 2020
  A new study highlights the high rate of diagnostic errors and serious consequences.
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  COVID-19: Multisystem Inflammatory Syndrome in Pediatrics
  Medscape Education Clinical Briefs June 26, 2020
  Multisystem inflammatory syndrome linked to COVID-19 in children resembles atypical Kawasaki disease and toxic shock syndrome.
  
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  COVID-19: What Do We Know About Hypercoagulation?
  Medscape Education Clinical Briefs June 12, 2020
  How to protect patients with COVID-19 from coagulopathy.
  
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• Top 10 Patient Safety Concerns for 2019
  Medscape Education Clinical Briefs April 26, 2019
  New guidelines highlights top 10 patient safety concerns.
  
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• UTI in the Elderly: Antibiotics Is Key
  Medscape Education Clinical Briefs April 26, 2019
  For elderly persons with UTIs, withholding or delaying antibiotics is linked to significant increases in bloodstream infection and all-cause mortality compared with immediate antibiotics.
  
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• Staph Infections Still a Deadly Concern, per CDC
  Medscape Education Clinical Briefs April 26, 2019
  In 2017, there were 119,000 total and 20,000 fatal cases of Staphylococcal bloodstream infections in the United States; lack of progress may reflect worsening compliance with infection prevention recommendations.
  
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• Is Sepsis-Associated Mortality Often Preventable?
  Medscape Education Clinical Briefs April 05, 2019
  Death associated with sepsis is rarely because of preventable errors, a new study shows.
  
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• Antibiotic Use in Sepsis: Is Shorter better?
  Medscape Education Clinical Briefs February 01, 2019
  New study suggests similar outcomes for 7 vs 14 days of antibiotic treatment for gram-negative bacteremia.
  
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• Can Antimicrobial Stewardship Decrease Sepsis in the NICU?
  Medscape Education Clinical Briefs September 01, 2017
  A new study finds benefits for an antimicrobial stewardship program in the neonatal intensive care unit in that such a program can reduce cases of late-onset sepsis.
  
  
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• Does Short-Term Oral Steroid Use Carry Serious Risk?
  Medscape Education Clinical Briefs June 28, 2017
  One-fifth of adults in a commercially insured US plan received short-term oral corticosteroids during a 3-year period, with an associated increased risk for adverse events.
  
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• CDC Cites Sepsis as a "Medical Emergency"
  Medscape Education Clinical Briefs September 22, 2016
  The Centers for Disease Control and Prevention encourages recognition of sepsis as a medical emergency and delivers means to prevent serious infection.
  
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• SCCM Issues New Criteria for Sepsis, Septic Shock Definition
  Medscape Education Clinical Briefs March 17, 2016
  The Society of Critical Care Medicine and the European Society of Intensive Care Medicine have issued evidence-based, updated definitions for sepsis and septic shock.
  
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• Updated IDSA Treatment Guidelines for Candidiasis
  Medscape Education Clinical Briefs February 03, 2016
  First-line treatment of candidemia should be aggressive using an echinocandin, according to updated treatment guidelines for Candida infections from the Infectious Diseases Society of America.
  
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• Study Compares Beta-Lactams with Vancomycin for MSSA Infection
  Medscape Education Clinical Briefs July 15, 2015
  In this retrospective cohort study, beta-lactams showed superiority to vancomycin for definitive therapy of methicillin-susceptible Staphylococcus aureus bloodstream infection.
  
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